RESEARCH PROJECTS
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“My Life” – co-producing self-management resources with people with dementia
Contracted centre: University of Exeter
Status: Active
Duration: 01 years 08 months
A qualitative study into the care & support experiences of individuals from African Caribbean backgrounds with diagnosis of dementia, living in Wales
Contracted centre: Cardiff University
Status: Active
Duration: 03 years 11 months
Ageing in Place with dementia: contextual scoping of underserved communities in the North East of England
Contracted centre: University of Newcastle
Status: Active
Duration: 00 years 11 months
Alzheimer s disease and the frontotemporal dementias: an integrated clinical neuroscience approach
Contracted centre: University of Cambridge
Status: Completed
Duration: 10 years 03 months
An exploration of patient experiences around diagnosis and treatment of dementia: implications for service development
Contracted centre: Hertfordshire PCT
Status: Completed
Duration: 01 years 08 months
Are multiple mechanisms involved in FTLD-TDP pathologensis: will one drug fit all?
Contracted centre: University College London
Status: Completed
Duration: 03 years 11 months
Associations between late-life depression and dementia: A large retrospective cohort study
Contracted centre: King's College London
Status: Completed
Duration: 00 years 01 months
Atherosclerosis, the brain and vascular dementia – the role of inflammation in neurovascular function
Contracted centre: University of Sheffield
Status: Active
Duration: 03 years 00 months
Biostatistics and functional genomics in dementia
Contracted centre: UK Dementia Research Institute at Cardiff University
Status: Active
Duration: 83 years 03 months
Blood-brain barrier dysfunction and risk of dementia following blood-stream infections
Contracted centre: Cardiff University
Status: Active
Duration: 02 years 11 months
Building research capacity to promote risk reduction and living well with dementia amongst minority ethnic communities
Contracted centre: University of Bradford
Status: Active
Duration: 01 years 09 months
Can damage to brain blood vessels explain symptoms of atrial fibrillation?
Contracted centre: University of Birmingham
Status: Completed
Duration: 02 years 00 months
Carer and patient-led development of recommendations for people with dementia returning home from hospital: understanding what is important
Contracted centre: University Hospitals Coventry and Warwickshire NHS Trust
Status: Completed
Duration: 01 years 11 months
Centre for prevention of stroke and dementia.
Contracted centre: University of Oxford
Status: Active
Duration: 06 years 02 months
Circadian dysfunction in the early stages of Alzheimer’s disease – Sleep theme
Contracted centre: Imperial College London
Status: Active
Duration: 00 years 00 months
Cognitive archaeology: identifying and measuring the presymptomatic phase of dementia
Contracted centre: St George's University of London
Status: Completed
Duration: 04 years 00 months
Consequences of ethnic differences in cardiometabolic disease in older age: the Southall And Brent Revisited (SABRE) tri-ethnic population cohort
Contracted centre: University College London
Status: Completed
Duration: 05 years 00 months
CRISPR-Cas9 genetic screens for novel synaptic maintenance genes and therapeutic targets
Contracted centre: University of Cambridge
Status: Active
Duration: 00 years 00 months
Dementia prevention, modifiable psychosocial risk factors of dementia: intervention, late-life depression: anxiety: early detection (Provisional)
Contracted centre: University College London
Status: Active
Duration: 03 years 00 months
DETERMinants of quality of life, care and costs, and consequences of INequalities in people with Dementia and their family carers
Contracted centre: University of Sussex
Status: Active
Duration: 00 years 08 months
Determinants of visit-to-visit variability in blood pressure and the related risks of stroke and dementia.
Contracted centre: University of Oxford
Status: Completed
Duration: 02 years 06 months
Determining the causes and consequences of brain amyloidosis, atrophy and cerebrovascular disease: a longitudinal amyloid-PET/MRI study of the MRC British 1946 birth cohort
Contracted centre: University College London
Status: Active
Duration: 05 years 00 months
Developing a novel system of care targetting risk factors for five manifestations of frailty to maintain the independence of older people in hospital and post-discharge.
Contracted centre: Bradford Teaching Hospitals NHS Foundation Trust
Status: Completed
Duration: 01 years 05 months
Developing a sustainable platform to understand the primary care, public health and social care needs for dementia, with a focus on underserved populations
Contracted centre: University of Cambridge
Status: Active
Duration: 00 years 11 months
Developing the African Turquoise killifish (N. furzeri) as a model for Alzheimer’s Disease
Contracted centre: University of Bath
Status: Active
Duration: 00 years 11 months
Differential display proteomics for drug discovery and diagnostics for Alzheimer s disease
Contracted centre: King's College London
Status: Completed
Duration: 03 years 00 months
Dissecting macroglial-neuronal crosstalk in C9ORF72 Frontotemporal dementia/ amyotrophic lateral sclerosis
Contracted centre: UK Dementia Research Institute at University of Edinburgh
Status: Active
Duration: 83 years 03 months
Dissecting the role of endothelial insulin-like growth factor-1 signalling in the vascular and metabolic complications of obesity-induced type 2 diabetes mellitus
Contracted centre: University of Leeds
Status: Completed
Duration: 03 years 00 months
Downsized cell-dervied peptides as potent inhibitors of aS Toxicity
Contracted centre: University of Bath
Status: Completed
Duration: 04 years 03 months
Effective clinical cancer treatment, care and management for people with comorbid cancer and dementia: understanding population demographics and intervention priorities and outcomes
Contracted centre: Leeds Teaching Hospitals NHS Trust
Status: Completed
Duration: 01 years 02 months
Epidemiological neuropathology of dementia – The Cognitive Function and Ageing Neuropathology Study
Contracted centre: University of Sheffield
Status: Completed
Duration: 05 years 00 months
Exploring and supporting everyday life with a rare dementia – understanding symptoms, developing strategies and sharing stories
Contracted centre: University College London
Status: Active
Duration: 02 years 00 months
Feasibility study: To assess whether reducing periodontal infection (gum disease) slows the progression of cognitive impairment associated with Alzheimer’s disease.
Contracted centre: University Hospitals Bristol and Weston NHS Foundation Trust
Status: Completed
Duration: 02 years 11 months
Frontotemporal dementia disease mechanisms
Contracted centre: UK Dementia Research Institute at University College London
Status: Active
Duration: 04 years 03 months
Home or hospital for people with dementia and one or more other multimorbidities: what is the potential to reduce avoidable emergency admissions?
Contracted centre: University Hospitals Bristol and Weston NHS Foundation Trust
Status: Completed
Duration: 01 years 05 months
How are patient and caregiver participation in health and social care shaped by experienced burden of treatment and social inequalities? A qualitative synthesis
Contracted centre: London School of Hygiene & Tropical Medicine
Status: Active
Duration: 02 years 06 months
Identification and Care of Patients at Risk of Post-Stroke Dementia
Contracted centre: University of Newcastle upon Tyne
Status: Completed
Duration: 04 years 11 months
Identifying Disease Mechanisms Caused by Endocytic Genes in Late Onset Alzheimer’s Disease
Contracted centre: Cardiff University
Status: Active
Duration: 02 years 11 months
Identifying neuroprotective mechanisms against genomic instability accrual in ageing and neurodegeneration
Contracted centre: University of Cambridge
Status: Active
Duration: 00 years 00 months
Impact of COVID-19 on people newly diagnosed with dementia and their family carers, a mixed method study nested in DETERMIND
Contracted centre: University of Plymouth
Status: Completed
Duration: 07 years 03 months
Implications of attachment relationships for the social and emotional well-being of older people, people with dementia, and family caregivers.
Contracted centre: Bangor University
Status: Completed
Duration: 01 years 09 months
Improving care for people with dementia in acute hospitals: development and feasibility study of rules- of -thumb to promote comfort and decrease distress
Contracted centre: University College London Hospitals NHS Foundation Trust
Status: Completed
Duration: 03 years 02 months
Improving Diagnosis And Measurement Of Progression In Dementia: Longitudinal Clinical And MRI Studies
Contracted centre: University College London
Status: Completed
Duration: 05 years 04 months
Improving our understanding of vascular mild cognitive impairment and vascular dementia
Contracted centre: Swansea University
Status: Active
Duration: 00 years 00 months
Interaction of Rab8 with OCRL1: Synaptic growth function in Frontotemporal Dementia and the Neurodevelopmental Disorder Lowe Syndrome
Contracted centre: University of York
Status: Active
Duration: 02 years 11 months
Investigating nervous system stability using a gene-edited ovine model of dementia
Contracted centre: University of Edinburgh
Status: Active
Duration: 02 years 11 months
Investigating relationships between genes, pathologies, and neurodegeneration in dementia
Contracted centre: University of Edinburgh
Status: Active
Duration: 00 years 00 months
Investigating the mechanisms of altered cortical excitability in frontotemporal dementia and amyotrophic lateral sclerosis
Contracted centre: King's College London
Status: Active
Duration: 02 years 11 months
Investigating the role of tau in dementia using patient-derived cell models: distinct mechanisms or common endpoint?
Contracted centre: University College London
Status: Completed
Duration: 03 years 11 months
Is blood-brain barrier dysfunction in Alzheimer’s disease driven by altered cellular metabolism?
Contracted centre: University of Dundee
Status: Active
Duration: 02 years 11 months
JPND LOss of neurotrophic factors in neurodegenerative DEmentias: Back to the crossroads of proteins
Contracted centre: University of Cambridge
Status: Active
Duration: 02 years 11 months
JPND The locus coeruleus: at the crossroad of dementia syndromes
Contracted centre: King's College London
Status: Active
Duration: 02 years 11 months
Life course aetiology of dementia and cognitive decline: improving causal inference
Contracted centre: University of Bristol
Status: Active
Duration: 02 years 11 months
Lifestyle Factors in Dementia and Cognitive Impairment in England and China: The Role of Sleep and Physical Activity
Contracted centre: University College London
Status: Active
Duration: 02 years 11 months
Linking genetic, epidemiology and metabolic phenotyping in dementia in the context of aging, environment and lifestyle
Contracted centre: UK Dementia Research Institute at Imperial College London
Status: Active
Duration: 83 years 03 months
Linking genetic, epidemiology and metabolic phenotyping in dementia in the context of aging, environment and lifestyle
Contracted centre: Imperial College London
Status: Active
Duration: 00 years 00 months
Mechanisms of Alzheimer’s disease development in Down syndrome
Contracted centre: University College London
Status: Active
Duration: 00 years 00 months
Mechanisms of neuronal loss in dementia: Role of matrix metalloproteinases in the degradation of the perineuronal net
Contracted centre: University of Bradford
Status: Completed
Duration: 03 years 02 months
Metabolic control of amyloid formation and synapse loss in dementia (Molecular amyloidosis & synaptopathy)
Contracted centre: UK Dementia Research Institute at King’s College London
Status: Active
Duration: 04 years 11 months
Modelling the potential population-level impact of modifying dementia risk factors using data from the Cognitive Function and Ageing Study
Contracted centre: University of Cambridge
Status: Completed
Duration: 00 years 11 months
Mortality and health service use in dementia and MCI- a mixed methods study
Contracted centre: King's College London
Status: Completed
Duration: 03 years 06 months
Multiscale and multimodal brain network changes causing Parkinson’s dementia
Contracted centre: University College London
Status: Active
Duration: 07 years 11 months
Neural system failure in dementia
Contracted centre: UK Dementia Research Institute at University College London
Status: Active
Duration: 04 years 11 months
On TReND: Mild Traumatic Brain Injury and the Contentious Reimagining of Alzheimer Disease-Related Dementias as Environmental Diseases
Contracted centre: University of Sheffield
Status: Completed
Duration: 04 years 11 months
Oral health and Alzheimer’s disease
Contracted centre: University of Bristol
Status: Active
Duration: 00 years 00 months
Predicting neurodegeneration after traumatic brain injury: a longtitudinal study of enviormental risk factor for Alzheimer’s disease
Contracted centre: Imperial College London
Status: Completed
Duration: 02 years 11 months
Predicting the risk of dementia using routine primary health care records
Contracted centre: University of Manchester
Status: Completed
Duration: 01 years 11 months
Prevention of dementia by targeting risk factors
Contracted centre: University College London
Status: Active
Duration: 03 years 00 months
Psychosocial support for people affected by Genetic and Non-Memory Led Dementias: developing digital provision and understanding the role of existing TALKing therapy services
Contracted centre: University College London Hospitals NHS Foundation Trust
Status: Completed
Duration: 04 years 11 months
Rescuing neurotrophic signalling through Rab10: a novel therapeutic target for Alzheimer’s disease.
Contracted centre: University College London
Status: Active
Duration: 02 years 11 months
Restoring axonal transport deficits as a therapeutic strategy for neurodegenerative diseases
Contracted centre: University College London
Status: Active
Duration: 00 years 00 months
Roles of protein SUMOylation in AMPA receptor trafficking, synaptic dysfunction and cognitive impairment in dementia
Contracted centre: University of Bristol
Status: Active
Duration: 03 years 11 months
Second Joint Stroke Association/BHF Programme Grant – How intensively should we treat blood pressure in established cerebral small vessel disease?
Contracted centre: University of Cambridge
Status: Completed
Duration: 05 years 00 months
SERVED Memory: Feasibility study of Screening & Enhanced Risk management for Vascular Event related Decline in Memory
Contracted centre: Norfolk and Norwich University Hospitals NHS Foundation Trust
Status: Completed
Duration: 03 years 00 months
Sex differences in Cognitive Performance, Cognitive Decline, and Risk of Dementia: A Lifecourse Approach
Contracted centre: University College London
Status: Active
Duration: 03 years 00 months
Small vessel diseases and vascular contributions to neurodegeneration and dementia
Contracted centre: UK Dementia Research Institute at University of Edinburgh
Status: Active
Duration: 83 years 03 months
Social determinants of dementia: A cross-country investigation between UK and Japan
Contracted centre: University College London
Status: Completed
Duration: 01 years 11 months
STrategies for Older People living in care homes to prevent Urinary Tract Infection: a realist synthesis of the evidence
Contracted centre: University of Southampton
Status: Completed
Duration: 01 years 05 months
Systematic reviews of interventions which target modifiable risk factors for dementia
Contracted centre: University of Oxford
Status: Completed
Duration: 02 years 05 months
Taking the long view: Identification of plasma protein biomarkers for dementia risk
Contracted centre: University College London
Status: Active
Duration: 04 years 11 months
Targeting TDP-43 meditated neurodegeneration for therapitic benefit in dementia
Contracted centre: King's Collefe London, Institute of Psychiatry, Psychology & Neuroscience
Status: Active
Duration: 02 years 11 months
The Dementia Engagement & Empowerment Project
Status: Active
Duration: 00 years 00 months
The relationship between later life depression and Alzheimer’s disease: bystander or participant?
Contracted centre: University of Bristol
Status: Active
Duration: 00 years 00 months
The role of capillary pericytes and LRP-1 in Parkinson’s disease and dementia
Contracted centre: University College London
Status: Active
Duration: 03 years 11 months
The Role of Extracellular Vesicles in Post-Stroke Vascular Dysfunction
Contracted centre: University of Oxford
Status: Active
Duration: 02 years 11 months
The role of social work in supporting people living with dementia in recent migrant populations to maximise quality of life
Contracted centre: King's College London
Status: Active
Duration: 00 years 11 months
The role of tau in synapse survival and its relevance to Alzheimer’s disease
Contracted centre: University of Edinburgh
Status: Active
Duration: 04 years 11 months
The systemic approach on the investigation of the association of cardiometabolic risk factors and dementia
Contracted centre: Imperial College London
Status: Active
Duration: 04 years 08 months
The Whitehall II study – can controlling heart disease risk factors result in healthy aging?
Contracted centre: University College London
Status: Completed
Duration: 04 years 00 months
Understanding the Contributions of Multiple Pathologies to Dementia in the BDR Programme
Contracted centre: Univsersity of Newcastle
Status: Completed
Duration: 03 years 00 months
Understanding the Contributions of Multiple Pathologies to Dementia in the BDR Programme
Contracted centre: University of Newcastle
Status: Completed
Duration: 03 years 00 months
Understanding the factors that influence why people with dementia make transitions from the community to acute hospital care settings in the last months of life: a retrospective cohort study
Contracted centre: King's College London
Status: Completed
Duration: 05 years 06 months
Understanding the link between sport and dementia risk
Status: Completed
Duration: 10 years 05 months
Understanding the views of older adults and people living with Mild Cognitive Impairment on driving and fitness to drive
Contracted centre: University of Sheffield
Status: Completed
Duration: 01 years 03 months
Unravelling the molecular basis of the association of genetic variation in the clusterin gene with risk of Alzheimer’s disease
Contracted centre: Cardiff University School of Medicine
Status: Active
Duration: 02 years 11 months
Using genetics to explore the pathophysiology of cerebral small vessel disease
Contracted centre: University of Cambridge
Status: Completed
Duration: 05 years 00 months
Using genetics to identify dementia risk factors.
Contracted centre: University of Bristol
Status: Active
Duration: 00 years 00 months
Using multisensory culture boxes to promote public health guidance and to support the wellbeing of people with dementia in care homes.
Contracted centre: University of Exeter
Status: Completed
Duration: 01 years 07 months
Using visual dysfunction to understand dementia in Parkinson’s disease
Contracted centre: University College London
Status: Active
Duration: 06 years 03 months
Vascular dementia: failure of fluid drainage from cerebral white matter (Joint funding with Stroke Association and Alzheimer’s Society for Advancing Care and Treatment of Vascular Dementia (ACT-VAD))
Contracted centre: University of Southampton
Status: Completed
Duration: 03 years 00 months
What happens during the transition from informal to formal homecare for a person living with dementia? An exploratory qualitative study.
Contracted centre: University of Dundee
Status: Active
Duration: 06 years 04 months
What is good for your heart is good for your brain: A mixed methods study on reducing dementia risk in UK Primary Care
Contracted centre: University College London
Status: Active
Duration: 00 years 00 months