RESEARCH PROJECTS

“My Life” – co-producing self-management resources with people with dementia

Contracted centre: University of Exeter
Status: Active
Duration: 01 years 08 months

Ageing in Place with dementia: contextual scoping of underserved communities in the North East of England

Contracted centre: University of Newcastle
Status: Active
Duration: 00 years 11 months

Alzheimer s disease and the frontotemporal dementias: an integrated clinical neuroscience approach

Contracted centre: University of Cambridge
Status: Completed
Duration: 10 years 03 months

An exploration of patient experiences around diagnosis and treatment of dementia: implications for service development

Contracted centre: Hertfordshire PCT
Status: Completed
Duration: 01 years 08 months

Are multiple mechanisms involved in FTLD-TDP pathologensis: will one drug fit all?

Contracted centre: University College London
Status: Completed
Duration: 03 years 11 months

Associations between late-life depression and dementia: A large retrospective cohort study

Contracted centre: King's College London
Status: Completed
Duration: 00 years 01 months

Atherosclerosis, the brain and vascular dementia – the role of inflammation in neurovascular function

Contracted centre: University of Sheffield
Status: Active
Duration: 03 years 00 months

Biostatistics and functional genomics in dementia

Contracted centre: UK Dementia Research Institute at Cardiff University
Status: Active
Duration: 83 years 03 months

Blood-brain barrier dysfunction and risk of dementia following blood-stream infections

Contracted centre: Cardiff University
Status: Active
Duration: 02 years 11 months

Building research capacity to promote risk reduction and living well with dementia amongst minority ethnic communities

Contracted centre: University of Bradford
Status: Active
Duration: 01 years 09 months

Can damage to brain blood vessels explain symptoms of atrial fibrillation?

Contracted centre: University of Birmingham
Status: Completed
Duration: 02 years 00 months

Carer and patient-led development of recommendations for people with dementia returning home from hospital: understanding what is important

Contracted centre: University Hospitals Coventry and Warwickshire NHS Trust
Status: Completed
Duration: 01 years 11 months

Centre for prevention of stroke and dementia.

Contracted centre: University of Oxford
Status: Active
Duration: 06 years 02 months

Circadian dysfunction in the early stages of Alzheimer’s disease – Sleep theme

Contracted centre: Imperial College London
Status: Active
Duration: 00 years 00 months

Cognitive archaeology: identifying and measuring the presymptomatic phase of dementia

Contracted centre: St George's University of London
Status: Completed
Duration: 04 years 00 months

CRISPR-Cas9 genetic screens for novel synaptic maintenance genes and therapeutic targets

Contracted centre: University of Cambridge
Status: Active
Duration: 00 years 00 months

Determinants of visit-to-visit variability in blood pressure and the related risks of stroke and dementia.

Contracted centre: University of Oxford
Status: Completed
Duration: 02 years 06 months

Developing a novel system of care targetting risk factors for five manifestations of frailty to maintain the independence of older people in hospital and post-discharge.

Contracted centre: Bradford Teaching Hospitals NHS Foundation Trust
Status: Completed
Duration: 01 years 05 months

Developing the African Turquoise killifish (N. furzeri) as a model for Alzheimer’s Disease

Contracted centre: University of Bath
Status: Active
Duration: 00 years 11 months

Differential display proteomics for drug discovery and diagnostics for Alzheimer s disease

Contracted centre: King's College London
Status: Completed
Duration: 03 years 00 months

Dissecting macroglial-neuronal crosstalk in C9ORF72 Frontotemporal dementia/ amyotrophic lateral sclerosis

Contracted centre: UK Dementia Research Institute at University of Edinburgh
Status: Active
Duration: 83 years 03 months

Downsized cell-dervied peptides as potent inhibitors of aS Toxicity

Contracted centre: University of Bath
Status: Completed
Duration: 04 years 03 months

Epidemiological neuropathology of dementia – The Cognitive Function and Ageing Neuropathology Study

Contracted centre: University of Sheffield
Status: Completed
Duration: 05 years 00 months

Exploring and supporting everyday life with a rare dementia – understanding symptoms, developing strategies and sharing stories

Contracted centre: University College London
Status: Active
Duration: 02 years 00 months

Feasibility study: To assess whether reducing periodontal infection (gum disease) slows the progression of cognitive impairment associated with Alzheimer’s disease.

Contracted centre: University Hospitals Bristol and Weston NHS Foundation Trust
Status: Completed
Duration: 02 years 11 months

Frontotemporal dementia disease mechanisms

Contracted centre: UK Dementia Research Institute at University College London
Status: Active
Duration: 04 years 03 months

Home or hospital for people with dementia and one or more other multimorbidities: what is the potential to reduce avoidable emergency admissions?

Contracted centre: University Hospitals Bristol and Weston NHS Foundation Trust
Status: Completed
Duration: 01 years 05 months

How are patient and caregiver participation in health and social care shaped by experienced burden of treatment and social inequalities? A qualitative synthesis

Contracted centre: London School of Hygiene & Tropical Medicine
Status: Active
Duration: 02 years 06 months

Identification and Care of Patients at Risk of Post-Stroke Dementia

Contracted centre: University of Newcastle upon Tyne
Status: Completed
Duration: 04 years 11 months

Identifying Disease Mechanisms Caused by Endocytic Genes in Late Onset Alzheimer’s Disease

Contracted centre: Cardiff University
Status: Active
Duration: 02 years 11 months

Identifying neuroprotective mechanisms against genomic instability accrual in ageing and neurodegeneration

Contracted centre: University of Cambridge
Status: Active
Duration: 00 years 00 months

Impact of COVID-19 on people newly diagnosed with dementia and their family carers, a mixed method study nested in DETERMIND

Contracted centre: University of Plymouth
Status: Completed
Duration: 07 years 03 months

Improving care for people with dementia in acute hospitals: development and feasibility study of rules- of -thumb to promote comfort and decrease distress

Contracted centre: University College London Hospitals NHS Foundation Trust
Status: Completed
Duration: 03 years 02 months

Improving Diagnosis And Measurement Of Progression In Dementia: Longitudinal Clinical And MRI Studies

Contracted centre: University College London
Status: Completed
Duration: 05 years 04 months

Improving our understanding of vascular mild cognitive impairment and vascular dementia

Contracted centre: Swansea University
Status: Active
Duration: 00 years 00 months

Investigating nervous system stability using a gene-edited ovine model of dementia

Contracted centre: University of Edinburgh
Status: Active
Duration: 02 years 11 months

Investigating relationships between genes, pathologies, and neurodegeneration in dementia

Contracted centre: University of Edinburgh
Status: Active
Duration: 00 years 00 months

Investigating the mechanisms of altered cortical excitability in frontotemporal dementia and amyotrophic lateral sclerosis

Contracted centre: King's College London
Status: Active
Duration: 02 years 11 months

Investigating the role of tau in dementia using patient-derived cell models: distinct mechanisms or common endpoint?

Contracted centre: University College London
Status: Completed
Duration: 03 years 11 months

Is blood-brain barrier dysfunction in Alzheimer’s disease driven by altered cellular metabolism?

Contracted centre: University of Dundee
Status: Active
Duration: 02 years 11 months

JPND LOss of neurotrophic factors in neurodegenerative DEmentias: Back to the crossroads of proteins

Contracted centre: University of Cambridge
Status: Active
Duration: 02 years 11 months

JPND The locus coeruleus: at the crossroad of dementia syndromes

Contracted centre: King's College London
Status: Active
Duration: 02 years 11 months

Life course aetiology of dementia and cognitive decline: improving causal inference

Contracted centre: University of Bristol
Status: Active
Duration: 02 years 11 months

Lifestyle Factors in Dementia and Cognitive Impairment in England and China: The Role of Sleep and Physical Activity

Contracted centre: University College London
Status: Active
Duration: 02 years 11 months

Linking genetic, epidemiology and metabolic phenotyping in dementia in the context of aging, environment and lifestyle

Contracted centre: UK Dementia Research Institute at Imperial College London
Status: Active
Duration: 83 years 03 months

Linking genetic, epidemiology and metabolic phenotyping in dementia in the context of aging, environment and lifestyle

Contracted centre: Imperial College London
Status: Active
Duration: 00 years 00 months

Mechanisms of Alzheimer’s disease development in Down syndrome

Contracted centre: University College London
Status: Active
Duration: 00 years 00 months

Mechanisms of neuronal loss in dementia: Role of matrix metalloproteinases in the degradation of the perineuronal net

Contracted centre: University of Bradford
Status: Completed
Duration: 03 years 02 months

Metabolic control of amyloid formation and synapse loss in dementia (Molecular amyloidosis & synaptopathy)

Contracted centre: UK Dementia Research Institute at King’s College London
Status: Active
Duration: 04 years 11 months

Mortality and health service use in dementia and MCI- a mixed methods study

Contracted centre: King's College London
Status: Completed
Duration: 03 years 06 months

Multiscale and multimodal brain network changes causing Parkinson’s dementia

Contracted centre: University College London
Status: Active
Duration: 07 years 11 months

Neural system failure in dementia

Contracted centre: UK Dementia Research Institute at University College London
Status: Active
Duration: 04 years 11 months

Oral health and Alzheimer’s disease

Contracted centre: University of Bristol
Status: Active
Duration: 00 years 00 months

Predicting the risk of dementia using routine primary health care records

Contracted centre: University of Manchester
Status: Completed
Duration: 01 years 11 months

Prevention of dementia by targeting risk factors

Contracted centre: University College London
Status: Active
Duration: 03 years 00 months

Psychosocial support for people affected by Genetic and Non-Memory Led Dementias: developing digital provision and understanding the role of existing TALKing therapy services

Contracted centre: University College London Hospitals NHS Foundation Trust
Status: Completed
Duration: 04 years 11 months

Rescuing neurotrophic signalling through Rab10: a novel therapeutic target for Alzheimer’s disease.

Contracted centre: University College London
Status: Active
Duration: 02 years 11 months

Restoring axonal transport deficits as a therapeutic strategy for neurodegenerative diseases

Contracted centre: University College London
Status: Active
Duration: 00 years 00 months

Roles of protein SUMOylation in AMPA receptor trafficking, synaptic dysfunction and cognitive impairment in dementia

Contracted centre: University of Bristol
Status: Active
Duration: 03 years 11 months

SERVED Memory: Feasibility study of Screening & Enhanced Risk management for Vascular Event related Decline in Memory

Contracted centre: Norfolk and Norwich University Hospitals NHS Foundation Trust
Status: Completed
Duration: 03 years 00 months

Sex differences in Cognitive Performance, Cognitive Decline, and Risk of Dementia: A Lifecourse Approach

Contracted centre: University College London
Status: Active
Duration: 03 years 00 months

Small vessel diseases and vascular contributions to neurodegeneration and dementia

Contracted centre: UK Dementia Research Institute at University of Edinburgh
Status: Active
Duration: 83 years 03 months

Social determinants of dementia: A cross-country investigation between UK and Japan

Contracted centre: University College London
Status: Completed
Duration: 01 years 11 months

STrategies for Older People living in care homes to prevent Urinary Tract Infection: a realist synthesis of the evidence

Contracted centre: University of Southampton
Status: Completed
Duration: 01 years 05 months

Systematic reviews of interventions which target modifiable risk factors for dementia

Contracted centre: University of Oxford
Status: Completed
Duration: 02 years 05 months

Taking the long view: Identification of plasma protein biomarkers for dementia risk

Contracted centre: University College London
Status: Active
Duration: 04 years 11 months

Targeting TDP-43 meditated neurodegeneration for therapitic benefit in dementia

Contracted centre: King's Collefe London, Institute of Psychiatry, Psychology & Neuroscience
Status: Active
Duration: 02 years 11 months

The Dementia Engagement & Empowerment Project

Status: Active
Duration: 00 years 00 months

The relationship between later life depression and Alzheimer’s disease: bystander or participant?

Contracted centre: University of Bristol
Status: Active
Duration: 00 years 00 months

The role of capillary pericytes and LRP-1 in Parkinson’s disease and dementia

Contracted centre: University College London
Status: Active
Duration: 03 years 11 months

The Role of Extracellular Vesicles in Post-Stroke Vascular Dysfunction

Contracted centre: University of Oxford
Status: Active
Duration: 02 years 11 months

The role of social work in supporting people living with dementia in recent migrant populations to maximise quality of life

Contracted centre: King's College London
Status: Active
Duration: 00 years 11 months

The role of tau in synapse survival and its relevance to Alzheimer’s disease

Contracted centre: University of Edinburgh
Status: Active
Duration: 04 years 11 months

The systemic approach on the investigation of the association of cardiometabolic risk factors and dementia

Contracted centre: Imperial College London
Status: Active
Duration: 04 years 08 months

The Whitehall II study – can controlling heart disease risk factors result in healthy aging?

Contracted centre: University College London
Status: Completed
Duration: 04 years 00 months

Understanding the Contributions of Multiple Pathologies to Dementia in the BDR Programme

Contracted centre: Univsersity of Newcastle
Status: Completed
Duration: 03 years 00 months

Understanding the Contributions of Multiple Pathologies to Dementia in the BDR Programme

Contracted centre: University of Newcastle
Status: Completed
Duration: 03 years 00 months

Understanding the link between sport and dementia risk

Status: Completed
Duration: 10 years 05 months

Understanding the views of older adults and people living with Mild Cognitive Impairment on driving and fitness to drive

Contracted centre: University of Sheffield
Status: Completed
Duration: 01 years 03 months

Unravelling the molecular basis of the association of genetic variation in the clusterin gene with risk of Alzheimer’s disease

Contracted centre: Cardiff University School of Medicine
Status: Active
Duration: 02 years 11 months

Using genetics to explore the pathophysiology of cerebral small vessel disease

Contracted centre: University of Cambridge
Status: Completed
Duration: 05 years 00 months

Using genetics to identify dementia risk factors.

Contracted centre: University of Bristol
Status: Active
Duration: 00 years 00 months

Using visual dysfunction to understand dementia in Parkinson’s disease

Contracted centre: University College London
Status: Active
Duration: 06 years 03 months

What is good for your heart is good for your brain: A mixed methods study on reducing dementia risk in UK Primary Care

Contracted centre: University College London
Status: Active
Duration: 00 years 00 months