Understanding the Contributions of Multiple Pathologies to Dementia in the BDR Programme

Status / Stage
1 September 2019 -
1 September 2022
Duration (calculated)
03 years 00 months
Alzheimer's Research UK
Funding Amount
Funder/Grant study page
Alzheimer's Research UK
Contracted Centre
University of Newcastle
Principal Investigator
Prof Alan Thomas
PI Contact
WHO Catergories
Tools and methodologies for interventions
Understanding risk factors
Understanding Underlying Disease
Disease Type
Dementia (Unspecified)

CPEC Review Info
Reference ID226
ResearcherReside Team


Status / StageCompleted
Start Date20190901
End Date20220901
Duration (calculated) 03 years 00 months
Funder/Grant study pageAlzheimer's Research UK
Contracted CentreUniversity of Newcastle
Funding Amount£71,208.87


Under the supervision of Prof Alan Thomas and with the support of his colleagues at the university, a PhD student will use data from the Brains for Dementia Research Programme to look at the relationship between the results of clinical tests and the different diseases that cause dementia.They will be using a range of sophisticated statistical methods to investigate which diseases and disease combinations have larger effects on cognitive decline and mood.The PhD student will also investigate the impact of disease location in the brain, and the significance of the hallmark proteins.This project will increase our understanding of how the different diseases interact to cause the decline of thinking skills associated with dementia.This knowledge is crucial for scientists conducting future drug trials.