Predicting neurodegeneration after traumatic brain injury: a longtitudinal study of enviormental risk factor for Alzheimer’s disease

Status / Stage
1 June 2017 -
31 May 2020
Duration (calculated)
02 years 11 months
Alzheimer's Research UK
Funding Amount
Funder/Grant study page
Alzheimer's Research UK
Contracted Centre
Imperial College London
Contracted Centre Webpage
Principal Investigator
Dr Neil Graham
PI Contact
WHO Catergories
Tools and methodologies for interventions
Understanding risk factors
Understanding Underlying Disease
Disease Type
Alzheimer's Disease (AD)

CPEC Review Info
Reference ID232
ResearcherReside Team


Status / StageCompleted
Start Date20170601
End Date20200531
Duration (calculated) 02 years 11 months
Funder/Grant study pageAlzheimer's Research UK
Contracted CentreImperial College London
Contracted Centre Webpage
Funding Amount£238,563.06


Working with 40 patients with traumatic brain injury (TBI), Dr Neil Graham at Imperial College London will investigate whether brain scans and the protein, neurofilament light (NFL) measured with blood tests soon after an injury could help predict future memory problems. Dr Graham will also carefully compare patterns of brain degeneration following TBI with those seen in the early stages of Alzheimer’s. His team wants to see if the same brain areas are affected and whether TBI could increase someone’s risk of Alzheimer’s by making these regions more vulnerable to the damaging processes that cause the disease.