Predicting neurodegeneration after traumatic brain injury: a longtitudinal study of enviormental risk factor for Alzheimer’s disease
Status / Stage
CompletedDates
1 June 2017 -31 May 2020
Duration (calculated)
02 years 11 monthsFunder(s)
Alzheimer's Research UKFunding Amount
£238,563.06Funder/Grant study page
Alzheimer's Research UKContracted Centre
Imperial College LondonContracted Centre Webpage
Principal Investigator
Dr Neil GrahamPI Contact
neil.graham@imperial.ac.ukWHO Catergories
Tools and methodologies for interventionsUnderstanding risk factors
Understanding Underlying Disease
Disease Type
Alzheimer's Disease (AD)CPEC Review Info
| Reference ID | 232 |
|---|---|
| Researcher | Reside Team |
| Published | 12/06/2023 |
Data
| Status / Stage | Completed |
|---|---|
| Start Date | 20170601 |
| End Date | 20200531 |
| Duration (calculated) | 02 years 11 months |
| Funder/Grant study page | Alzheimer's Research UK |
| Contracted Centre | Imperial College London |
| Contracted Centre Webpage | |
| Funding Amount | £238,563.06 |
Aims
Working with 40 patients with traumatic brain injury (TBI), Dr Neil Graham at Imperial College London will investigate whether brain scans and the protein, neurofilament light (NFL) measured with blood tests soon after an injury could help predict future memory problems. Dr Graham will also carefully compare patterns of brain degeneration following TBI with those seen in the early stages of Alzheimer’s. His team wants to see if the same brain areas are affected and whether TBI could increase someone’s risk of Alzheimer’s by making these regions more vulnerable to the damaging processes that cause the disease.