The Role of Extracellular Vesicles in Post-Stroke Vascular Dysfunction

Status / Stage
1 September 2020 -
31 August 2023
Duration (calculated)
02 years 11 months
Alzheimer's Research UK
Funding Amount
Funder/Grant study page
Alzheimer's Research UK
Contracted Centre
University of Oxford
Principal Investigator
Dr Yvonne Couch
PI Contact
WHO Catergories
Models of Disease
Understanding risk factors
Understanding Underlying Disease
Disease Type
Dementia (Unspecified)

CPEC Review Info
Reference ID223
ResearcherReside Team


Status / StageActive
Start Date20200901
End Date20230831
Duration (calculated) 02 years 11 months
Funder/Grant study pageAlzheimer's Research UK
Contracted CentreUniversity of Oxford
Funding Amount£237,246.00


Will investigate whether brain cells send out signals that change how blood vessels behave. They will study whether these signals are delivered to blood vessels through tiny information packages sent out by nerve cells. The researchers will work to understand how these tiny information packages change after a stroke and how that affects the signals that they send to blood vessels. By increasing our understanding how the brain and blood vessels communicate after a stroke, scientists hope that they may find new clues as to how we can reduce the risk of dementia.