RESEARCH PROJECTS
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Cardiovascular mechanisms linked to cerebral amyloid β deposition and cognitive decline: A substudy of INSIGHT 46
Contracted centre: University College London
Status: Completed
Duration: 02 years 07 months
Cerebrovascular and inflamm-ageing link to neurodegeneration and dementia
Contracted centre: University of Edinburgh
Status: Active
Duration: 00 years 00 months
Complement in Alzheimer’s disease: from gene discovery to mechanisms and better drugs
Contracted centre: University of Cardiff
Status: Active
Duration: 00 years 00 months
Computational modelling for understanding mechanisms of Alzheimer’s disease progression
Contracted centre: University College London
Status: Active
Duration: 03 years 11 months
Developing new ways to study and test treatments for small vessel disease in vascular dementia
Contracted centre: University of Edinburgh
Status: Completed
Duration: 04 years 11 months
Developing the African Turquoise killifish (N. furzeri) as a model for Alzheimer’s Disease
Contracted centre: University of Bath
Status: Active
Duration: 00 years 11 months
Development of a 3D model of the cortex for investigation of neurodegenerative diseases
Contracted centre: Aston University
Status: Active
Duration: 04 years 04 months
Do astrocytes store more fat when our brain gets older: a new target for dementia?
Contracted centre: University of Nottingham
Status: Completed
Duration: 00 years 01 months
Does brain trauma cause premature ageing of the nervous system?
Contracted centre: University of Liverpool
Status: Active
Duration: 02 years 11 months
Enhancing cognition through the menopausal transition in at-risk ‘APOE4’ carriers by fatty acid and hormonal modulation.
Contracted centre: University of East Anglia
Status: Active
Duration: 02 years 11 months
Epigenetic regulation of environmental and genetic risk in neurodegenerative disease
Contracted centre: Imperial College London
Status: Active
Duration: 00 years 00 months
Exploring the role of epigenetic changes in Alzheimer’s disease
Contracted centre: University of Exeter
Status: Active
Duration: 00 years 00 months
Genetic mechanisms underlying tauopathies
Contracted centre: University of Edinburgh
Status: Active
Duration: 00 years 00 months
Glial-neuronal homeostatic mechanisms with amyloid pathology
Contracted centre: Imperial College London
Status: Active
Duration: 00 years 00 months
Human stem cell models of Alzheimer’s disease
Contracted centre: University of Cambridge
Status: Completed
Duration: 05 years 11 months
Identifying Disease Mechanisms Caused by Endocytic Genes in Late Onset Alzheimer’s Disease
Contracted centre: Cardiff University
Status: Active
Duration: 02 years 11 months
Inducing age-related changes in microglia as a model for Alzheimer’s disease
Contracted centre: University of Bath
Status: Completed
Duration: 03 years 09 months
Investigating the cellular reaction to amyloid beta and Tau
Contracted centre: University College London
Status: Active
Duration: 00 years 00 months
Investigating the role of tau in dementia using patient-derived cell models: distinct mechanisms or common endpoint?
Contracted centre: University College London
Status: Completed
Duration: 03 years 11 months
Local interactions between tau and synapses in dementia
Contracted centre: University of Bristol
Status: Completed
Duration: 00 years 01 months
Micro-circuit homeostasis in early Alzheimer’s disease
Contracted centre: Imperial College London
Status: Active
Duration: 00 years 00 months
Mining a common food compound, Epicatechin, for a new Alzheimer’s disease treatment
Contracted centre: University of Bath
Status: Completed
Duration: 02 years 10 months
Modelling dementia progression based on machine learning and simulations
Contracted centre: Newcastle University
Status: Active
Duration: 02 years 11 months
Multi-modal machine learning of large-scale genetic, biologic, and brain imaging data for identification of therapeutic targets and early prediction
Contracted centre: Imperial College London
Status: Active
Duration: 03 years 11 months
Multi-task Learning for Predicting Alzheimer’s Disease Progression
Contracted centre: University of Sheffield
Status: Active
Duration: 03 years 05 months
Single molecule nucleocytoplasmic transport dynamics in FTD/ALS
Contracted centre: King's College London
Status: Active
Duration: 00 years 00 months
Small vessel disease and vascular contributions to neurodegeneration and dementia
Contracted centre: University of Edinburgh
Status: Active
Duration: 00 years 00 months
Structure-function relationship in neurodegeneration
Contracted centre: University College London
Status: Active
Duration: 00 years 00 months
Synaptic repair mechanisms for the diseased brain
Contracted centre: University of Edinburgh
Status: Active
Duration: 00 years 00 months
The molecular causes and consequences of tauopathy in Alzheimer’s disease and Frontotemporal dementia
Contracted centre: University College London
Status: Active
Duration: 00 years 00 months
The Role of Extracellular Vesicles in Post-Stroke Vascular Dysfunction
Contracted centre: University of Oxford
Status: Active
Duration: 02 years 11 months
The role of inherited and acquired mitochondrial DNA mutations in Dementia with Lewy Bodies.
Contracted centre: Newcastle University
Status: Completed
Duration: 01 years 04 months
The role of sleep in protecting against amyloid and glial pathology in dementia
Contracted centre: UK Dementia Research Institute at Imperial College London
Status: Active
Duration: 83 years 03 months
The role of tau in synapse survival and its relevance to Alzheimer’s disease
Contracted centre: University of Edinburgh
Status: Active
Duration: 00 years 00 months
The role of tau in synapse survival and its relevance to Alzheimer’s disease
Contracted centre: University of Edinburgh
Status: Active
Duration: 04 years 11 months
Towards an in vivo functional dissection of the role of microglia and macrophages in Alzheimer’s disease aetiology
Contracted centre: University of Cardiff
Status: Active
Duration: 00 years 00 months
Understanding the effects of the diabetes type 2 drug Metformin on models of Alzheimer’s disease
Contracted centre: University College London
Status: Active
Duration: 03 years 00 months
Understanding the molecular basis of tau aggregation and spreading
Contracted centre: University of Cambridge
Status: Active
Duration: 00 years 00 months
Understanding the role of neurodegenerative disease risk genes in the ageing nervous system
Contracted centre: University of Cardiff
Status: Active
Duration: 00 years 00 months
Unravelling the molecular basis of the association of genetic variation in the clusterin gene with risk of Alzheimer’s disease
Contracted centre: Cardiff University School of Medicine
Status: Active
Duration: 02 years 11 months
Using graph networks to identify microbiome-based therapeutics for neurodegenerative diseases
Contracted centre: University College London
Status: Active
Duration: 04 years 00 months
Using stem cells to model protein quality control dysfunction in dementia
Contracted centre: Cardiff University
Status: Active
Duration: 00 years 00 months
What does the human face tell the human brain?
Contracted centre: University College London
Status: Active
Duration: 04 years 03 months