Is blood-brain barrier dysfunction in Alzheimer’s disease driven by altered cellular metabolism?
Status / Stage
ActiveDates
1 May 2022 -30 April 2025
Duration (calculated)
02 years 11 monthsFunder(s)
Alzheimer's Research UKFunding Amount
£234,484.05Funder/Grant study page
Alzheimer's Research UKContracted Centre
University of DundeeContracted Centre Webpage
Principal Investigator
Dr Fiona McleanPI Contact
f.mclean@dundee.ac.ukPI ORCID
0000-0003-0946-4891WHO Catergories
Understanding risk factorsUnderstanding Underlying Disease
Disease Type
Alzheimer's Disease (AD)CPEC Review Info
| Reference ID | 216 |
|---|---|
| Researcher | Reside Team |
| Published | 12/06/2023 |
Data
| Status / Stage | Active |
|---|---|
| Start Date | 20220501 |
| End Date | 20250430 |
| Duration (calculated) | 02 years 11 months |
| Funder/Grant study page | Alzheimer's Research UK |
| Contracted Centre | University of Dundee |
| Contracted Centre Webpage | |
| Funding Amount | £234,484.05 |
Aims
This project aims to discover when and how the build-up of amyloid causes the blood-brain barrier to breakdown. The aim is to find ways to reverse these changes in the blood-brain barrier early in the very early stages of Alzheimer’s disease and keep the brain healthy.