Identifying Disease Mechanisms Caused by Endocytic Genes in Late Onset Alzheimer’s Disease
Status / Stage
ActiveDates
1 January 2021 -31 December 2023
Duration (calculated)
02 years 11 monthsFunder(s)
Alzheimer's Research UKFunding Amount
£172,976.00Funder/Grant study page
Alzheimer's Research UKContracted Centre
Cardiff UniversityPrincipal Investigator
Dr Natalie Connor-RobsonPI Contact
Connor-robsonNL@cardiff.ac.ukWHO Catergories
Models of DiseaseUnderstanding risk factors
Understanding Underlying Disease
Disease Type
Alzheimer's Disease (AD)CPEC Review Info
| Reference ID | 218 |
|---|---|
| Researcher | Reside Team |
| Published | 12/06/2023 |
Data
| Status / Stage | Active |
|---|---|
| Start Date | 20210101 |
| End Date | 20231231 |
| Duration (calculated) | 02 years 11 months |
| Funder/Grant study page | Alzheimer's Research UK |
| Contracted Centre | Cardiff University |
| Funding Amount | £172,976.00 |
Aims
Dr Natalie Connor-Robson will use cutting edge stem cell technology to unpick how these Alzheimer’s risk genes change the behaviour of nerve cells and microglia. She will also investigate how the changes in these genes affect how these cells respond to amyloid, a hallmark protein of Alzheimer’s disease. By better understanding how these risk genes impact brain cells, both in normal conditions and during Alzheimer’s disease, researchers may be able to identify new drug targets