Developing the African Turquoise killifish (N. furzeri) as a model for Alzheimer’s Disease

Status / Stage
Active
Dates
4 April 2022 -
3 April 2023
Duration (calculated)
00 years 11 months
Funder(s)
Alzheimer's Research UK
Funding Amount
£49,905.00
Funder/Grant study page
Alzheimer's Research UK
Contracted Centre
University of Bath
Contracted Centre Webpage
Principal Investigator
Dr Vasanata Subramanian
PI Contact
V.S.Subramanian@bath.ac.uk
PI ORCID
0000-0003-2463-545X
WHO Catergories
Models of Disease
Understanding risk factors
Understanding Underlying Disease
Disease Type
Alzheimer's Disease (AD)
Frontotemporal Dementia (FTD)

CPEC Review Info
Reference ID219
ResearcherReside Team
Published12/06/2023

Data

Status / StageActive
Start Date20220404
End Date20230403
Duration (calculated) 00 years 11 months
Funder/Grant study pageAlzheimer's Research UK
Contracted CentreUniversity of Bath
Contracted Centre Webpage
Funding Amount£49,905.00

Aims

Aims to introduce features of Alzheimer’s and frontotemporal dementia to these fish so that researchers will have a new way to study these diseases.Adapting the killifish for dementia research will be a useful asset for future studies. These may include identifying new targets for therapeutics or even testing possible treatments for Alzheimer’s or frontotemporal dementia. The short lifespan of the killifish makes it easier to repeat experiments and allows researchers to gather more data. This will accelerate dementia research efforts and could help researchers make even more exciting discoveries.