UKDRI INDEX.PHP
Untangling toxic aggregates in neurodegeneration with the ubiquitin-proteasome system
published on Thursday, June 29th, 2023
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Developing biosensors to detect infections and monitor dementia progression
published on Thursday, June 29th, 2023
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Glial-neuronal homeostatic mechanisms with amyloid pathology
published on Thursday, June 29th, 2023
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Complement in Alzheimer’s disease: from gene discovery to mechanisms and better drugs
published on Thursday, June 29th, 2023
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Towards an in vivo functional dissection of the role of microglia and macrophages in Alzheimer’s disease aetiology
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Epigenetic pathways in healthy ageing and neurodegeneration
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Robotics to enhance independence & safety
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Micro-circuit homeostasis in early Alzheimer’s disease
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Epigenetic regulation of environmental and genetic risk in neurodegenerative disease
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Single molecule nucleocytoplasmic transport dynamics in FTD/ALS
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Dissecting macroglial-neuronal crosstalk in C9ORF72 FTD/ALS
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Non-cell autonomous mechanisms of synapse pathology
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Structure-function relationship in neurodegeneration
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Bioelectronic systems for intervention in dementia
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Biostatistics and functional genomics
published on Thursday, June 29th, 2023
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How do microglia regulate myelin integrity and cognitive function in health and ageing?
published on Thursday, June 29th, 2023
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Harnessing immunity to target protein aggregation.
published on Thursday, June 29th, 2023
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Targeting novel anti-complement drugs to the brain for therapy of dementia.
published on Thursday, June 29th, 2023
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Immune mechanisms of synaptic function and pathology
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Altered RNA metabolism in neurodegeneration
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Circadian dysfunction in the early stages of Alzheimer’s disease – Sleep theme
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Understanding the molecular mechanisms of endocytic genes and polygenic risk in late onset Alzheimer’s disease
published on Thursday, June 29th, 2023
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Simple questions about neurodegenerative disease: where? when? how?
published on Thursday, June 29th, 2023
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From Patient to Bench and Back: Clinical Resources, Accelerating Therapies
published on Thursday, June 29th, 2023
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Understanding the role of neurodegenerative disease risk genes in the ageing nervous system
published on Thursday, June 29th, 2023
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Synaptic repair mechanisms for the diseased brain
published on Thursday, June 29th, 2023
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Linking genetic, epidemiology and metabolic phenotyping in dementia in the context of aging, environment and lifestyle
published on Thursday, June 29th, 2023
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Understanding and repairing pathological neural circuits in Alzheimer’s disease
published on Thursday, June 29th, 2023
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Synapse weakening in the pathophysiology of Alzheimer’s disease
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Restoring axonal transport deficits as a therapeutic strategy for neurodegenerative diseases
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Astrocytes as an upstream modulator and downstream effector of neurodegenerative pathology
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Fluid biomarkers for neurodegenerative diseases
published on Thursday, June 29th, 2023
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Real-time interrogation of neural circuit dynamics underpinning cognition and its collapse in dementia
published on Thursday, June 29th, 2023
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Identifying novel strategies to restore the microglial homeostatic phenotype and modulate neuroinflammation in dementia
published on Thursday, June 29th, 2023
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Small vessel disease and vascular contributions to neurodegeneration and dementia
published on Thursday, June 29th, 2023
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Analysis of neurodegeneration
published on Thursday, June 29th, 2023
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Myeloid cells in neurodegenerative diseases
published on Thursday, June 29th, 2023
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The molecular causes and consequences of tauopathy in Alzheimer’s disease and Frontotemporal dementia
published on Thursday, June 29th, 2023
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Genetic mechanisms underlying tauopathies
published on Thursday, June 29th, 2023
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Frontotemporal dementia and amyotrophic lateral sclerosis disease mechanisms
published on Thursday, June 29th, 2023
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Exploring the utility of synaptic markers in frontotemporal dementia
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Understanding cell type gene regulation in ageing-related brain disorders
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Cerebrovascular and inflamm-ageing link to neurodegeneration and dementia
published on Thursday, June 29th, 2023
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Microglial mechanisms influencing susceptibility and resilience to dementia-causing disease
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Investigating the cellular reaction to amyloid beta and Tau
published on Thursday, June 29th, 2023
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Developing point-of-care biosensing technology for the detection of blood neurodegenerative biomarkers
published on Thursday, June 29th, 2023
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Architecture, function and dysfunction of astrocyte-vasculature interactions
published on Thursday, June 29th, 2023
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Investigating relationships between genes, pathologies, and neurodegeneration in dementia
published on Thursday, June 29th, 2023
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Proteostatic mechanisms in FTD and ALS
published on Thursday, June 29th, 2023
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The role of tau in synapse survival and its relevance to Alzheimer’s disease
published on Thursday, June 29th, 2023
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Understanding the molecular basis of tau aggregation and spreading
published on Thursday, June 29th, 2023
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Identification of novel pathways that induce autophagy to enable neuroprotection
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Using technology to improve the lives of people living with dementia
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Role of ER dynamics and morphological regulation in neuronal health and disease
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CRISPR-Cas9 genetic screens for novel synaptic maintenance genes and therapeutic targets
published on Thursday, June 29th, 2023
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Mechanisms of Alzheimer’s disease development in Down syndrome
published on Thursday, June 29th, 2023
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Identifying neuroprotective mechanisms against genomic instability accrual in ageing and neurodegeneration
published on Thursday, June 29th, 2023
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