Harnessing knowledge of lifespan biological, health, environmental and psychosocial mechanisms of cognitive frailty for integrated interventions
Study Code / Acronym
CFINAward Number
BB/W018322/1Status / Stage
ActiveDates
14 February 2022 -13 February 2024
Duration (calculated)
01 years 11 monthsFunder(s)
BBSRC (UKRI)Funding Amount
£176,605.00Funder/Grant study page
BBSRC UKRIContracted Centre
Lancaster UniversityContracted Centre Webpage
Principal Investigator
Professor Carol Ann HollandPI Contact
c.a.holland@lancaster.ac.ukPI ORCID
0000-0001-7109-6554WHO Catergories
Methodologies and approaches for risk reduction researchTools and methodologies for interventions
Disease Type
Cognitive ImpairmentCPEC Review Info
| Reference ID | 378 |
|---|---|
| Researcher | Reside Team |
| Published | 12/06/2023 |
Data
| Study Code / Acronym | CFIN |
|---|---|
| Award Number | BB/W018322/1 |
| Status / Stage | Active |
| Start Date | 20220214 |
| End Date | 20240213 |
| Duration (calculated) | 01 years 11 months |
| Funder/Grant study page | BBSRC UKRI |
| Contracted Centre | Lancaster University |
| Contracted Centre Webpage | |
| Funding Amount | £176,605.00 |
Abstract
The Cognitive Frailty Interdisciplinary Network (CFIN) will promote multidisciplinary research tackling development of age-related cognitive frailty and associated reduced healthspan and quality of life. This is both a major societal challenge in our ageing populations and a research challenge to integrate findings from multiple fields into effective prevention and therapeutic interventions across the life course that are implementable in real contexts. The primary goal of this proposal is thus network building across disciplines (including biology, neuroscience, psychology, epidemiology, social science and citizen engagement) and groups (researchers, clinicians, learned societies, business, clinicians, support organisations, older adults and carers) to foster transformative collaborative research for the purpose of better understanding and alleviation of the burdens of cognitive frailty. Network creation will be achieved by forming an external advisory group (EAG) and convening meetings, building membership through existing networks of investigators and members, and by use of social media and judicious linking of a network website. The CFIN will be fully activated at a networking conference at 6 months. Specific outcomes in addition to the EAG and researcher network will be the production of a cross disciplinary evidence synthesis of biological mechanisms and exogenous factors as related to cognitive frailty, identifying gaps, to inform creation of interdisciplinary collaborations with specific goals. Specific small projects will be funded, forming the basis of further Network-based funding proposals to external funders. There will also be a consensus document produced using a two stage Delphi process bringing together membership expertise on the most evidentially supported multi-dimensional interventions for cognitive frailty. Both papers will be submitted for publication. A Mentorship programme and summer school for ECRs will also be supported.
Aims
This network aims to bridge the gaps between basic, clinical and social science research to foster the translation of the scientific understanding of ageing. The objectives are focused on building and operationalising an important network in this area across disciplines including Biology, neuroscience, psychology, epidemiology, social science and citizen engagement, with an array of linked network support organisations including the NHSA and the National Innovation Centre for Ageing.