Aims

Investigating one of the hallmark proteins of frontotemporal dementia.Dr Tammaryn Lashley will tease apart this complexity, zeroing in on the key changes that cause nerve cells to die. The team is focusing on a particular protein called TDP-43, which is found in the brain in about half of those with FTD. Researchers don’t yet know all the different ways that TDP-43 can cause nerve cell damage, so understanding more about the key steps in the disease will help in the search for new treatments.